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Vaccine for middle ear infection tested in infants

Health

CBC News || March 06, 2006

A new vaccine may help reduce middle ear infections, a common problem in toddlers, researchers say.

Czech researchers tested a potential vaccine for middle ear infection, or otitis media.

The infection is usually mild, causing fever and pain, but it can sometimes result in complications like hearing loss.

The infection often follows a cold and is common in young children. Treatment is usually antibiotics.



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Roman Prymula of the University of Defence, in Hradec Kralove, Czech Republic, and colleagues randomly assigned nearly 5,000 infants to receive three doses of the vaccine and a booster or a vaccine for hepatitis A as a control during the first six months of life.

"We found a reduction in ear, nose and throat specialist-confirmed episodes of acute otitis media by about a third in infants in the vaccine group compared with controls," the team wrote in the March 4th issue of the medical journal The Lancet.

The vaccine also appeared to protect against middle ear infections caused by two leading bacterial pathogens, S. pneumoniae and a type of H. influenzae, the study said.

The study was sponsored by the vaccine's manufacturer, and many of the study's authors have ties to the company.

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