Some preschoolers can use Ritalin: Knowledge Driven Revolution

The first long-term U.S. government study of preschoolers who take Ritalin, the popular attention deficit disorder drug, warns of side-effects but also found benefits in children with severe problems.

The drug isn't approved for use in children under age six, and the researchers said those youngsters need close monitoring because preschoolers are more likely than older children to develop side effects.

The research was done because of concerns over reports that soaring numbers of very young children are being given psychiatric drugs, including Ritalin.

The study's message is, proceed with caution, said Dr. Thomas Insel, director of the National Institute of Mental Health.

"We're not talking about fidgety three-year-olds," said Insel, whose agency funded the study. The research involved children with severe cases of attention deficit hyperactivity disorder — cases that included hanging from ceiling fans, jumping off slides or playing with fire.

The researchers say the benefits of low-dose treatment outweigh the risks for these youngsters.

Safety not established, critic contends

But critics disputed that.

"I hope publication of this does not lead to more overprescribing," said Dr. Sidney Wolfe of the watchdog group Public Citizen. "The safety isn't adequately established, the efficacy even less."

About 40 per cent of children developed side effects and roughly 11 per cent dropped out because of problems including irritability, weight loss, insomnia and slowed growth.

Preschoolers on methylphenidate, or generic Ritalin, grew about half an inch less and gained about two pounds less than expected during the 70-week study.

Doctor calls study a catastrophe

"This is a catastrophe. It just opens up the way for drugging the younger kids," said Dr. Peter Breggin, a New York psychiatrist and longtime critic of psychiatric drug use in children.

Breggin said the research is part of a marketing push by the drug industry to expand drug use to the youngest children.

The study appears in the November edition of the Journal of the American Academy of Child and Adolescent Psychiatry. Several of the researchers have financial ties to makers of ADHD drugs, including Ritalin.

Lead author Dr. Laurence Greenhill, a psychiatrist with Columbia University and New York State Psychiatric Institute, has been a paid speaker for most companies that make the drugs.

Roughly eight per cent of U.S. children have ADHD, including about three per cent of preschoolers. In Canada in 2005, two million prescriptions for stimulants such as Ritalin were written to treat ADHD.

Study outlines pros, cons

Previous research found that about one in 100 preschoolers had been prescribed Ritalin, which has only been approved for use in children aged six and older. Use in younger children is considered "off-label" but is not illegal.

Dr. David Fassler, a psychiatry professor at the University of Vermont, said the study does a good job of outlining pros and cons of Ritalin treatment in preschoolers.

"This is exactly the kind of information we need to help parents make informed decisions about treatment options for young children with ADHD," Fassler said.

The study included 10 weeks of behavioural treatment along with parent training and about one year of drug treatment. Nearly 300 families were enrolled, but many dropped out after the first phase, either because the behaviour treatment worked or because they didn't want to put their children on drugs.

The drug phase started with 165 children, more than a dozen dropped out because of side-effects.

Behaviour improvements were seen in children taking 7.5 to 30 milligrams daily, but the optimal dose was 14 milligrams daily — less than half the usual Ritalin dose for older children, Greenhill said.

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HOME Canadians Should Pay NOT to be Poisoned: NDP V for Vendetta - R for Reality Canadian Bird Flu Pandemic Looming ? Shill of the Week: Stephan Harper Aspartame: The Sweetest Killer Chicken Little Terrorist of the Week: Creating Fake Terrorists Shill of the Week: Paul Martin The Number 1 Reason YOU became a Slave	Some preschoolers can use Ritalin CBC News October 23, 2006 The first long-term U.S. government study of preschoolers who take Ritalin, the popular attention deficit disorder drug, warns of side-effects but also found benefits in children with severe problems. The drug isn't approved for use in children under age six, and the researchers said those youngsters need close monitoring because preschoolers are more likely than older children to develop side effects. The research was done because of concerns over reports that soaring numbers of very young children are being given psychiatric drugs, including Ritalin. The study's message is, proceed with caution, said Dr. Thomas Insel, director of the National Institute of Mental Health. "We're not talking about fidgety three-year-olds," said Insel, whose agency funded the study. The research involved children with severe cases of attention deficit hyperactivity disorder — cases that included hanging from ceiling fans, jumping off slides or playing with fire. The researchers say the benefits of low-dose treatment outweigh the risks for these youngsters. Safety not established, critic contends But critics disputed that. "I hope publication of this does not lead to more overprescribing," said Dr. Sidney Wolfe of the watchdog group Public Citizen. "The safety isn't adequately established, the efficacy even less." About 40 per cent of children developed side effects and roughly 11 per cent dropped out because of problems including irritability, weight loss, insomnia and slowed growth. Preschoolers on methylphenidate, or generic Ritalin, grew about half an inch less and gained about two pounds less than expected during the 70-week study. Doctor calls study a catastrophe "This is a catastrophe. It just opens up the way for drugging the younger kids," said Dr. Peter Breggin, a New York psychiatrist and longtime critic of psychiatric drug use in children. Breggin said the research is part of a marketing push by the drug industry to expand drug use to the youngest children. The study appears in the November edition of the Journal of the American Academy of Child and Adolescent Psychiatry. Several of the researchers have financial ties to makers of ADHD drugs, including Ritalin. Lead author Dr. Laurence Greenhill, a psychiatrist with Columbia University and New York State Psychiatric Institute, has been a paid speaker for most companies that make the drugs. Roughly eight per cent of U.S. children have ADHD, including about three per cent of preschoolers. In Canada in 2005, two million prescriptions for stimulants such as Ritalin were written to treat ADHD. Study outlines pros, cons Previous research found that about one in 100 preschoolers had been prescribed Ritalin, which has only been approved for use in children aged six and older. Use in younger children is considered "off-label" but is not illegal. Dr. David Fassler, a psychiatry professor at the University of Vermont, said the study does a good job of outlining pros and cons of Ritalin treatment in preschoolers. "This is exactly the kind of information we need to help parents make informed decisions about treatment options for young children with ADHD," Fassler said. The study included 10 weeks of behavioural treatment along with parent training and about one year of drug treatment. Nearly 300 families were enrolled, but many dropped out after the first phase, either because the behaviour treatment worked or because they didn't want to put their children on drugs. The drug phase started with 165 children, more than a dozen dropped out because of side-effects. Behaviour improvements were seen in children taking 7.5 to 30 milligrams daily, but the optimal dose was 14 milligrams daily — less than half the usual Ritalin dose for older children, Greenhill said. Read the full article here Broken Link? If the link to the original article is broken or has been altered you can view the article by clicking here. About KDR \| \| Home \| \| Weekly Features Archive	Weekly Features Archive
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