The Bulletin of the Atomic Scientists, which sets the clock, was founded in 1945 as a newsletter distributed among nuclear physicists concerned about nuclear war, and midnight originally symbolized a widespread nuclear conflict. The bulletin has grown into an organization focused more generally on manmade threats to human civilization.

"The dangers posed by climate change are nearly as dire as those posed by nuclear weapons," said Kennette Benedict, director of the bulletin.

Stephen Hawking, the renowned cosmologist and mathematician, told The Associated Press that global warming has eclipsed other threats to the planet, such as terrorism.

"Terror only kills hundreds or thousands of people," Hawking said. "Global warming could kill millions. We should have a war on global warming rather than the war on terror."

This is the first time the bulletin has explicitly addressed the threat from climate change.

"We are transforming, even ravaging the entire biosphere. These environmentally driven threats - threats without enemies - should loom as large as did the East-West divide during the Cold War era," said Martin Rees, president of the Royal Society, Britain's academy of science.

"Unless they rise higher on international agendas, remedial action may come too late," he added.

There is no actual Doomsday Clock in keeping with the bulletin's symbolic exercise. But the group has used several makeshift clocks or replicas over the years in logos, images and publications.

Since it was set to seven minutes to midnight in 1947, the Doomsday Clock has been moved 18 times, including Wednesday's adjustment. It came closest to midnight - just two minutes away - in 1953 after the successful test of a hydrogen bomb by the United States. It has been as far away as 17 minutes, set there in 1991 following the demise of the Soviet Union.

The decision to move the clock is made by the bulletin's board, composed of scientists and policy experts, in co-ordination with the group's sponsors, who include Hawking and science fiction writer Arthur C. Clarke.

Despite the organization's new focus on global warming, the prospect of nuclear war remained its primary concern, the bulletin's editor, Mark Strauss, told The AP.

"It's important to emphasize 50 of today's nuclear weapons could kill 200 million people," he said.

The organization floated a variety of proposals to help control the threat of nuclear proliferation and repeated a call to nuclear nations to whittle down their arsenals and reduce the launch readiness of their weapons.

Panelist Lawrence Krauss, a physics professor at Case Western Reserve University in Cleveland, criticized the use of military means to deal with nuclear proliferation and emphasized the use of diplomacy.

"If we want to address proliferation we want to do it in a unified way, and not with the sole country acting pre-emptively," he said.

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